Like Mary, my neck and back are screwed up bad. Work finally forced me out after a fall at work and now on disability retirement. I took the multiple pills a day but had issues with the spiking and falling pain levels; not to mention high blood pressure. I went on the 24/7 one pill a day. I am in slightly more pain but it is more evened out now. Blood pressure basically normal now. Like Mary said, you have to move around and do things. For me the nights are the worst with being up every hour or two from pain and sleeping on the floor half the time. Now some folks say opioids are being abused by others so now I have to jump through hoops and drive round trip 1 1/2 - 2 hours every month when sitting for more than 30 minutes becomes painful to see a pain doc. System is screwed up. Said it before, same argument anti gun folks make.