(Before I knew better)My testing with Lil'gun was with a 500S&W... and I found that the recoil and concusssion were a lot higher with lil'gun than h110. But when I chronoed the loads I found the the Lilgun load was actually slower in fps than the more managable h110 load.
I found that nothing worked as well in my 22 hornet as lil'gun and brass would last way longer than those loaded with 2400... maybe thats why they named it Lil'gun and not MagPistol
That being said.. if you have trouble finding powder and you can buy the big jug for $155. I say buy it. You will probly not shoot the 480 enough to burn your pistol up with it, Especially with the wrists hurting you. Most guys I know that shoot the 475's find that the 11-1200fps mark with a 400gr +/-is a good place to shoot them ( Mr. Linebaugh himself told me he likes them around 1150 with the 385gr.) ... still shoot the length of a brownbear.