I have had several, a couple of Contenders that would talk to me during a steel match. My 10" 357 Herrett lasted right at 500 rounds until it twisted the frame. Shooting it with the original little square wood grip, with the engraving plate on the base, would change your outlook. A 230 at 2,000 fps was tough, twisted, turned sideways and turned while coming up, all at the same instant. It was unpleasant for a fact. Ended up with a new frame and shooting cast 200s through it.
But I have seen a couple of incidents in 40+ years as a match director that stick. 44 Auto Mag showed up one match, shooter made it through 20 rounds, got tired, then on the first turkey, he could no longer steady the gun, so just reached up with his left hand, grabbed his wrist, before I could stop him, pulled the trigger, the bottom of the recoil system took the top of his left hand right off slick as a whistle. Now that smarted, a ride to the hospital on that one, for some serious stitching.