You need to come up with a couple things How much ammo ( preferably the same load) do you intend to load? How much time do you want to invest in this? Loading multiple calibers in large batches is easy on the 650. Extra tool heads can be set up for other calibers. The case feeder means your only handling bullets and pumping the handle. Spare primer tubes make that run longer before taking a break to fill them again. If you decide time is less important than ammo count then a smaller slower press may be the answer.
I started with a Coax for rifle and pistol. Up graded to a lee 1000 for a short time for pistol ( got really good at changing those nylon bushings) and went to a 650 for pistol with measure and case feeder. I then added a second 650 set up with a harrels measure for rifles. I have 15 primer tubes in a home made stand for both large and small primers. I modified the spent primer cups to a tygon tube ran to a gallon jug. and instead of the akro bin for loaded rounds I made a chute for loaded rounds to slide down dropping into a ammo can or box. The cup for the spent primers holds just over 100 primers the modified one for the tube saves emptying the primer cup every time you fill the primer tube. It actually saves emptying the primer cup altogether sldie the hose out of the jug when full and slide in a new jug every so often. ( I don't fill them as a gallon jug of spent primers is pretty heavy) The extra primer tubes are nice in that when they are empty you can sit down and take a break filling the tubes. Or better still have wife children or buddy fill tubes while your loading. This really picks up production. The slide saves the constant emptying of the loaded round bin and allows for ammo to go into the actual box its stored in. You may want the riser strong mount for this to have the slide high enough. Ive loaded .380 acp, 38 spl, 357 mag, 40 S&W, 10mm, 44 special, 44 mag, 45 acp and 45 colt. The .380 required some tinkering with the drop on the case feeder to keep the short cases from plugging the top falling sideways. Now with the spacers made it all trouble free. On the rifle press I loaded 223. 243. 308. 22-250. WHat I shot for high power. Once I mounted the Harrels measure I loaded my ammo for 200-600 yds on this 650. 1000 yds I loaded on the coax still. I loaded the season high power ammo in febuary and march. Not for a match but for the coming season. I never felt handicapped or an ammo issue loading with the 650s
Decide what your requirements are and quanities needed are. Then go from there. Dillons catalog has a good section on picking the right press for your needs also. This is THe Blue Press.