I use my 500 S & W with 95:5 Pb:Sn subsonic 600 grainers and a suppressor at ranges <100 yards out back of my house. I don't get near that devastation, but with head shots they go down instantly. Back in November I took a muley in the Ft. Peck area of Montana at 883 yards with a Hornady 143 grain ELD-X using my 6.5 Creedmoor. One shot, cold barrel, double lunged him. Ain't no way in the world his head would be mounted on my wall right now and his meat would be in my freezer with a cast bullet from any rifle. Later in the season I took 2 more whitetails with my Thompson Center flintlock at ~60 yards out behind the house in PA. That's a more reasonable range for cast lead. If lead was as good as jacketed, it would be still be in use by all the militaries in the world. Its a great hobby, just keep in mind the limitations and work within those bounds so your harvest is done ethically.