It takes 5000 to 7000 +/- psi to fully obturate a case to seal against the chamber wall. How much depends on the thickness of the case and how "hard" the brass is. Annealing thicker cases such as Starlines can help. With the 45 Colt i ran into the problem some years back when doing a thorough test of VV N32C powder with 200 gr cast bullets for cowboy action loads in a M92 Rossi. Withe many of the loads [also including several factory loads] I had gas escaping back and hitting my forehead. The gas blowback wasn't evident with revolvers or with the closed breach Contender I was using to measure the psi. However, incomplete obturation of the fired cases [Starline, Federal, Winchester and Remington] was very evident.
What I found from the data recorded with the Oehler m43 PBL was the faster the rise to peak pressure, the greater the obturation. What is needed to get complete obturation with 45 Colt cases that were FL sized with carbide dies while keeping the psi in the 14 - 15,000 range or less was to move the peak pressure point as close to the mouth of the cartridge case as possible. This was done by using the fastest and most easily ignitable burning powders generally available. The powders that performed best were Bullseye, 700X, WSP and Red Dot with charges in the 7 to 7.2 gr range under the 200 gr cast bullets. I also found those powders to give the best obturation at 14,000 psi or less with 250 gr +/- cast bullets. With lighter weight bullets the powder charges needed to increase but at full case obturation the psi exceeded 14,000. Bottom line is if you use a slower burning powder or one that doesn't ignite as quickly then you'll probably just have to put up with minimal case obturation.
I found not using a carbide sizer, which FL sized the case body, but instead to use an older steel FL sizer [mine is a RCBS] that just sizes the cases to the chamber spec taper. Yes, the cases need to be lubed. I clean the cases, use a spray lube on them, deprime/FL size with the RCBS die then a short cleaning to remove the lube and they are ready to load on my Dillon 550B with a Lee deprime die in station #1 to ensure the flash hole is clear. All my 45 Colt loads loaded as such give full obturation in my revolvers and M73 carbine.











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