I "started" my sons handgun shooting with a Savage .22 Long Rifle Single Shot Blue, 4” Barrel “Revolver” (S/n 50xxx), giving them ONLY .22 short ammo. Typical me, the barrel periodically had a bore-snake pulled through it -- I always stressed the need to ensure unobstructed barrels -- but, no more. Jump ahead a few years, I went on a fishing trip where I didn't wish to "hurt" or damage any handgun, but reckoned it would be astute to have one -- so I elected this Savage. Never giving it any thoughts, when we got to location I attempted to load in a plain-Jane .22 long rifle round -- and it would only chamber about 5/8th of the way!
It turned out that from the repeated .22 short firing my boys had done, a crusty ring was formed in the cylinder!
Back home, it took "forever and a day" before I had crud-ring reduced to enable long rifle rounds being chambered -- and there STILL is a very visible ring!
Hence -- in response to OP -- shoot away with shorts if you so wish -- BUT, I strongly suggest you pay attention to cylinder and,at the least, run a solvent-soaked brass bore brush through after each shooting session.
geo