I think 50 yards will be what I consider extreme range for my handgun loads, with maybe 80 to 100 yards for .357 and .44 through my lever actions. As per another suggestion here, I just need to compare results with "good" bullets and "rejects".
When I start loading for my .303 Uberti Stalking Rifle, I may be a little more picky, but I'll be looking for casual target shooting and deer accuracy out to an extreme of 200 yards.