For general purpose use I use mainly Alliant 2400 for magnum velocities in .44 magnum, .357 magnum, and heavy .45 Colt loads.
For standard velocities I use Hodgdon Universal. It's virtually a clone of Alliant Unique, but it meters better and it's cleaner. I used Unique before but no longer.
For hunting loads in my .357 magnum lever gun I use Hodgdon H110, since it achieves the greatest velocity without stressing anything.
I have never used Alliant Bullseye for anything in close to 50 years of reloading and never wanted to.