Many people, including myself, have extolled the so-called Skeeter Load: 7.5 grains of Unique with the 429421 in 44 Special case. In my 6.5" S&W 624 this goes ~975 FPS. I have personally verified this is an accurate load and a pleasant load. And it works pretty much with any ~255 grains SWC: the 429244, H&G 503, etc.
But has anyone taken any deer with it? At what range? What impact location? It seems like it should be adequate, but I am curious.