I've been on anti-inflammatiories for over 20 years. And I've spent most of this month on the referral-go-round due to heart and kidney problems. According to the cardiologist, both were caused by the anti-inflammatories. And he said that while there are several different types, they *all* cause problems over the long term.
I'd done my "due diligence" and read up on what I was taking when I got the prescriptions, but it never occurred to me to check back every few years and see if new data was available.