Well I might as well add my two cents to this gong show.
In college I aquired a combat masterpiece at a very nice price. I carried that thing everywhere. Woods load out was one 150gr Keith over a max load of 2400 followed by five normal 38 wad cutters. Figured for personal defense my best shot would be the first one, the rest were for small game. Grouse would usually sit still long enough to cycle the second round under the hammer then pop 'em. Any way...
I was hiking back to my dirt bike during deer season after scouting some fur territory. I came right from campus and had stashed the 38 in my saddle bags, rifle was not an option that trip. I stumbled across a spike horn, must have been the dumbest deer in the whole county. I stood still and he came with about seven yards. I waited until he turned his head to check his back trail then let him have it right behind the left ear. He dropped like a sack of taters. It was a lot of work getting his butt out of that swamp but at that time I really couldn't afford to pass up such an opportunity.
Looked a little odd riding into town with deer quarters stacked on the back of a KLR.