DoctorBill, Not Chargar, but I've used 16+ lbs. of WC 860, a ball powder which is almost the same as WC 872, and never had even an inkling of a problem with it. As Chargar mentioned, as long as the case capacity is >40 grs. and you use almost a caseful of it (with LR Mag. primers), there will be little chance of a secondary explosion. That means charging at least to the neck-shoulder junction, little/no compression, and NO fillers.*
*I tried WC 860 with and without spherical shot buffer in various .30cal. cartridges and found no benefit in doing so with one exception. To wit, in the 7.65 x 53mm Arg. Mau., using Ly. #314299, the addition of ~1cc spherical shot buffer allowed me to drop the powder charge to 43 grs. (from 44) and resulted in more efficient burning as evidenced by clean necks and little unburned powder in the fired cases.