8.0 grains of Unique has done well for me in 41 Magnum with the 212 grain Lyman SWC #410032, as has 8.0-9.0 grains of Herco. Herco gets the nod at 9.0 grains for most of my shooting these days. An all-day load, and it runs about 925-950 FPS from my 6"-6.5" barrels.