I have a number of military rifles that I dedicate to shooting only cast boolits. 7mm, 8mm, 30.06 and 303 all are reserved for cast boolits ONLY. Then there is my Winchester collection, 25/20, 32/20, 38/40, 44/40, 32/40 and 38/55, all never see anything but cast boolits. I once shot "J" boolits through the 30.06 and it was quite a long time and several cleanings before the guilt edged accuracy returned.
Now I keep my 'J' boolit rifles and " ONLY cast " seperated in order to prolong the excellent accuracy that I have managed to achieve.
Just like any rifle, they will wear out eventually, but how many rounds will that take? Those who compete regularly in cast competitions would be wise.