Very much so. Today I loaded some .458 500 grain round nose FMJ's subsonic's for a friend. They are at a book velocity of 1,000 fps. I compared the nose shape to some 452" 230 gain round nose FMJ's and they are almost identical. I have some 230's loaded to an actual velocity of 1,000 fps. Both will give a pass thru in most 2 legged SD situations with the wound channel and energy transfer being very similar except of a .006" diameter difference and the 500 grain not slowing down as much. The 500 grain has more than double the KE's and much greater penetration yet the wound channel and stopping power will be about equal for two legged targets. For something like a brown bear the greater penetration is highly beneficial.