Greg,
I have used JB weld in a number of applications related to motorcycle repair and that epoxy has never failed. The key is to have clean surfaces, hopefully not smooth as glass because you would like the epoxy to bond into the material. Pay attention to the drying time. Also if this is a vaulted ceiling then you might have trouble with the epoxy running out of the hole, due to gravity. In which case you might want to us an expansion type anchor.
Expansion anchors are good if you have the correct thickness of material to expand in to.
I would stay away from Gorilla glues as it expands considerably.
best
atr