Why choose? If that magnum piece works for 4-legged critters it should work equally well for the 2-legged variety.
Nothing says 'get outa my face' better than a 2-foot fireball and an equally impressive shockwave launching 1/2 oz of lead downrange with enough energy to lift the lead critter off the ground. One shot from that magnum will give a small crowd reason to pause and discuss who will assume the now-vacated position of leader. Considering the price of primers, it just seems more efficient.
By coincidence, a 44 mag with SWC's is my nightstand gun. And wouldn't ya know it, the one time I could have used it to defend against a black bear coming through the door I was out of the country and not able to have it with me.