I had a RBH in .45Colt when Taffin was still shooting heavy loads. I was loading heavy 255 and 300gn bullets in my Ruger and enjoying the 'manliness' of heavy recoil and large bullets striking the target. His article on wrist and elbow damage was what made me realize I was feeling the same symptoms in my arm. Instead of downloading I sold the gun. When I want to shoot 'downloaded' .45 I get out a 1911 Haven't shot another heavy big bore since.