I thought about asking first. Then I just tried it. All of the primers (32) were set by me, so I knew none were crimped. Just used some caution, hand over the primed cartridge while pulling the handle, safety glasses. Yea, I know but better my hand than an eye or neck. All small pistol, they came out no problem, no crushed primers or mangled anvils.
And if you ask, it was for a caliber I no longer have.
Some finesse is in order if you do this, I'm not saying it's safe for everyone. I made sure for each one that the remover stem fit into the flash hole, I'm sure that limits the danger.
I've not loaded more than 1000 in the last few years and only removed about 100, not one lost yet. (Well the carpet ate a couple and I've since found them.)