Hunting loads in my 92 45 Colt (originally a 454 Casull) use H110 propelling a Saeco 300-grain SWC-GC. The load was created first in my Freedom Arms 97 45 Colt. Although not pleasant ammunition to shoot in the FA 97, my Rossi 24-inch barrel transmutes the ammunition to what is accomplished when shooting a factory 300-grain 454 Casull cartridge from a 7.5-inch barreled revolver.
I have TiteGroup for light loads in the revolver. I haven't yet tried to find a load for the rifle. I observe that our purposes for handloading the rifles differ. I don't do much plinking or knock-around shooting with it. I have a Marlin 39 for that purpose. When we wander in Lolo National Forest and not deliberately hunting, firearms carried are still loaded up until they squeak. My friend is terrified of bears. "Terrified" is no exaggeration for her reaction. In a left-handed way, she's right. There are a lot of bears in the area. To make a long story less long, the Rossi and FA 97 combine as my version of the cowboy having Winchester 1873 and Colt SAA in 44-40. But my version functions somewhat better.
H110 and TiteGroup are the only powders I use. CCI Magnum large pistol primers are all that I use. Winchester and Starline brass are all that I use.
Hope something in this mishmash is helpful.