I loaded 5 rounds of 35 whelen using Large Pistol primers.
200gr FN cast 0.359/ 18.4 gr/2400 / G.I. Brass resized to 35 whelen
they shot as well as the same load using rifle primers, good group at 50 yds.
I did detect just a slight "lag" between the strike of the primer and full discharge, but not that affected the shooting.
In Freedom
atr