I've got a 20" blued Rossi .454 Casull, and I shoot .45 Colt through it all the time. I don't get any leading in mine whatsoever. I do clean it very well after every range session though. I think the issue isn't leading, but carbon buildup. Also, I think if it's an issue at all, it's with very tight (min SAAMI spec) chambers in high end revolvers such as the Freedom Arms model 83. Regardless, I've never had a problem with my Rossi. Maybe if I run through 200 rounds of .45 Colt and then try some full power .454 rounds without cleaning it could be a problem, I don't know.
With regard to accuracy, I notice no difference at all between .45 Colt and .454 Casull loads in mine.
Sam Sackett is 100% correct about the mag tube being threaded into the receiver on the .454 carbines (and the .480 Ruger carbines too). I wish they'd have done that for the .44 mag carbines. I've had the mag tube on my .44 carbine walk out on me during one range session. Once it happens, it will be easier for it to happen again, because the screw at the front of the mag tube which presses up against the underside of the barrel near the muzzle creates a big gouge as the tube walks out a little bit on each shot. I've tried various things which have helped to a small degree, but if it happens again on mine I may be forced to have a gunsmith weld up the underside of the barrel to build the material up again that the mag tube screw gouged out. Regardless, I can't emphasize enough what a great improvement it is to have the mag tube thread into the receiver.
If the two carbines are priced similarly, I wouldn't hesitate to grab the .454.
And several folks have pointed out that if you need more power than .45 Colt, just get a .45-70 Marlin. For me, the .454 was a much better choice than a .45-70. For one thing, I wanted something light and handy. The 1895 Marlin or an 1886 Winchester are booth a good bit beefier and heavier than the Rossi 92. Secondly, I've already got a pretty sizable investment in .45 Colt components and bullet casting gear--molds, sizing die, etc. The .45-70 is a completely new caliber I'd have to gear up for.
Anyway, just my $0.02.