Originally Posted by
memtb
. . .If the attacker is an animal, or a human with impaired thought processes (mental or drugs)....this offers a different situation. The humans may not show the typical human response of self preservation, and the drugs or mental impairment may slow the reaction to a fatal wound. In these situations, in my opinion, there is “no substitute for cubic inches”! Though, bullet placement, and bullet construction are still of paramount importance.....however, increased tissue damage (though permanent wound size and wound depth) are a plus. I don’t think that many of us, knowing without a doubt we would find ourselves in this scenario would choose a lesser cartridge over a large bore, much more powerful handgun!