Lee 358-158 RF. Big fan of this profile. Load and cast as you see fit.
Ive taken whitetail with a 357 gp100 and iron sights. Accuracy is key with the 357 so pick your most accurate loading, set a reasonable distance and practice. My distance was 25-30yrds. Last whitetail was 35yrds. Broke tge near shoulder, went through both lungs and lodged on the offside. 175lbs