It depends on what you are wanting to do. For example red dot/promo and Unique will make literally anything go bang. .32 acp to .45/70. I always have red dot or promo on hand.
Rifles are a different critter if you want more velocity. If you want neat little groups of holes on paper at 100 yards then promo or unique can get you there.
Right now I am chasing 2000+ fps in .308 and factory duplication ln .30-30. It seems that every burn rate of powder has an upper limit. Once you reach the speed limit on that group of powders you need to move on to the next slower group of powders. If I wanted to punch paper or kill cans fast shotgun powders would be all I ever needed.
Handguns have been much simpler. H110 or 296 has worked in ever .44 magnum I have ever had. Power pistol rules in .44 special and 9mm. 231 just kicks butt in .45 acp.
Hope this helps.
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