Dale I always look forward to what you have to say, and you don't need to qualify your statement.
Your 250 gr. Keith at 1200 fps is not a practice load, Hell, that will do it all.
Remember that LaunBaughs (spelling) wife and son took antelope and Mule deer at give or take 100 yards with complete pass through with Keith 260's at 900 fps.
In Keiths "6 guns" I am pretty sure he was shooting his 250's in 44/45 at 900 to 1000 fps at some short and extraordinary ranges that seemed to make him very happy, and if I remember correctly he had pass through most of the time.
Now if that kind of velocity from documented weight bullets by a couple of the greatest authorities on handguns is not qualified in itself, golly what the heck would be?