I own and shoot both revolvers and semi-autos. I reload my own cast and so far have had excellent results with that.
As far as caliber, I like to stick with common, easily obtained calibers. I currently load for 38 Special, 357 mag, 9mm, 40 S&W, and 45 ACP. My favorites are 38 Special, 9mm, and 45 ACP. I can't handle more powerful calibers due to arthritis in my wrists.
My handguns include several 38/357 revolvers, several 9mm semi-autos(Beretta, Taurus, 1911), one 9mm revolver(S&W 929 wonderful gun), and a couple of 45 ACP 1911 handguns.
My handguns tend to get a good workout every so often(mostly often) to maintain familiarity and proficiency plus I just enjoy using/shooting them. Any one gun won't see 5000 rounds a year but I shoot easily two to three times that much combined.
The only revolver type I have never had any luck with is single action revolvers(Ruger Blackhawks and Colt SSA clones). For some reason I just can't shoot them at all well and I have tried several different ones.
I probably already own the guns I will end up with.
I wanted to see if I was missing a good bet somewhere that I should try out, particularly since I have no experience with any striker fired pistol of any brand.
There is always something out there that I don't know about. The easiest way to find out is to ask.