First Marlin I ever purchased was in 2000 was a Marlin 1895M in 450 Marlin , the second I purchased very shortly there after was a 1895CB in 45-70 .
Over the course of time I've owned three Marlin's chambered for the 450 and eight for the 45-70 .
When one handloads for either of these cartridges in a post 1972 Marlin 1895 they can be pretty much loaded the same .
The 450 feeds in the loading port just a touch better then the 45-70 and 45-70 brass is easier to find .
If you handload it's kinda six of one and half a dozen of the other .
I like them both although I own neither any longer .