You don't want just a single characteristic called fluffy.
You want fluffy and the right burn rate at the same time.
Fluffy can be defined as the specific gravity of the powder. The LOWER the specific gravity the more space a grain of powder will take up in the case. Specific gravity is the mass of the powder per CC compared to water. The specific gravity of water is always 1 - that is 1 CC of water always weighs 1 gram.
Pick all the powders with the right burn rate to produce the best ballistics.
Then order the powders from the most dense to the least dense.
Measure the volume of your case to the base of the bullet.
The least dense powder with the right burn rate that fills the case would be ideal.
Use a loading manual to give you maximum charges.
Pick out a fluffy powder and see if the max charge fits. If it does not fit go to the next more dense powder on the list.
I used this method for picking a powder for the .45 ACP and wound up using HS 6.