so been reading a little on the subject. sounds like if the gas is blowing between the primer and the case then the case is suspect. if there is a hole in the primer then the primer itself could be faulty.
i had 9 out of 49 blow and it was a hole in the primer right at the bend/corner of the cup. the brass has been well used, about 6x fired. mostly med loads of 44mag, maybe 2 firings were hotter loads. this load, with all the failures, was 265g bullet, 9g Unique, Win LP. Otherwise the brass is in good shape. i've used these primers out of the same case for many other rounds with no problems. could it be that the pack of 100 is bad, or could it be the brass?