I just changed from Lyman Alox to SPG in one of my Lyman 450's. First I ran a batch of boolits with a stick of SPG through the reservoir until that first stick of SPG was all used up and the reservoir was empty. Then removed the H&I die, unbolted the press from the bench and ran boiling hot water into the H&I die hole in the press. While the press was still warm it took just a couple of Q-Tips and a shop towel to wipe out the rest of the Alox. Pretty simple. The key to changing lubes is to not waste the existing lube in the press.