.22, .357 or 10mm (depending on platform preference) .44Mag. Pick the weight you are scared enough to carry, and then you will know which caliber you are taking. Hmmm, am I 20, 32, or 48oz scared? Or for the .500 guys, am I 5.2lbs of scared to go out today? Not a knock on you gibson, those are the calibers I like at this moment...
It is never only about ballistics, it is also platform, size, and weight.
It isn't just black and white paper ballistics, either. IF a .357 was the same size and weight as a G20, and would do 180@1400 vs. the 10 doing 230@1100, which would be better? Same s.d., but one has the weight and size advantage, while the other has more velocity. What if the g20 was limited to 10 rd mags, would it change anything? Would the activity or weather conditions change your answer? (rhetorical questions, really, but make the point, I think.)