Before this gets to "deep" My thought is if you don't kow the payload weight how can you decide on a start load?
Lymans 358156 is a prime example. Read "Skeeter" Skelton for years, He claimed this mold made 150 grain boolits. When one was aqquired I find it casts 165 to 175 depending on alloy and the mold vintage!
At last I realized "Skeeter's" mold must have been an HP which, after I had Buckshot convert one for me, was exactly what came out of it, 150 grains!
I always cast, check payload weight and then work up a load from a selected start load from the manuals.
Never blown up a gun, never broke a gun ( from a load anyway) and never tried to make a magnum out of a caliber that wasn't.
Being safe is good.