I've used International to load .380's and was impressed with it. Gonna try it next in .38 Special. Keep it away from any high pressure cartridges tho', like 9mm, .40SW, or any of the magnums. Hodgdon's doesn't list any handgun loads because the powder is allegedly peaky and they don't trust it. Keep it under, say, 20000 psi and you should be fine.