I don't pretend to have all the mechanical wisdom about the 1911 pistol, that some on this thread have. I can tell you, that with a throated barrel and the 452423 seated out, as per my post to DougGuy, the pistol and load will do a grand job at killing White Tail deer at reasonable ranges. I suspect it would put a human down pretty quick with a fair hit. For social purposes, I would trust it more than a JHP.
I do realized the BD and other newer designs with a big meplat and rounded shoulders would probably work as well, but I have no need to buy new molds that will do the same as 452423.