My grandson shot his first deer this morning, a nice fat 5 point, with my Henry big boy in .45 colt using my load of 18.5 gr. A2400 and the Lee 452-255 WFN. He hit the spine just above the tenderloin, it had to be shot again. Both were pass through. Shot was around 40 yards. Him and his family were extremely happy for him as well as myself..