Very interesting thread; I like to read about getting old rifles shooting again, especially #2 rolling blocks.
You are right when you said earlier they are not large rifles and deserve to be used with caution. In my opinion they are just a touch larger than the typical boys rife, such as a #4 Remington, but an order of magnitude higher in quality.
I remember reading in Frank DeHass's book Single Shot Rifles and Actions (which I can't find right now) that the #2 is okay for .32-20, but not for the high speed rifle loads.
I believe the #2 was developed from the RRB pistols, and I have read that the centerfire breech block from one can be used to convert a RF #2 to centerfire. Don't believe it is a simple drop in switch; the firing pin still needs to be moved, and it takes a lot of work to make the extractor function properly. I know because that is the route I took with my .32.
If I had it to do over again I would either convert the original bb to centerfire, or buy one of the new bb castings.
I apologize for drifting the thread, but there always seems to be a lot of interest in #2 Remingtons.
Robert