Congrats on your new gun! Lots of good advice and experience here. I'll add my two cents...
I spend more time with my .45 BH than any of my other guns. I don't necessarily like it more, it's just something that happens.
I reamed out the throats and I also fire lapped mine. I've tried lots of loads and lots of different bullets. I echo what other said about settling on sane loads. At the age of 50, I just don't like dealing with the sore wrist that comes with the hot loads.
Anyway, though accuracy has always been good, I got my best from a load I developed with IMR 4227 and a Lyman boolit. It's in the pics below. Right now I'm shooting the same Lyman boolit with about 7.5 grains of Unique cause I have more of that powder and need to use it up. Truly great gun. If you're like me it'll never collect dust...
(Just had to throw this in too. I was given some blank powder which is not recommended for use in any loads involving lead. My experienced friend told me to just use it for light loads, so I did. Below is a group I got with the .45 BH at 15 yards using a light load of blank powder.)