Mmmmmm. . . .yeaaaaaahhhhhh. . .
As a wise armorer-instructor once told me "ALL guns are pieces of **** just waiting to fail on you". One thing I'm sure of is that revolvers are NOT infallible. Another is that a once-functional autoloader is usually A LOT easier to troubleshoot back into functionality than a once-functional wheelgun. There's a long string of consecutive engineering miracles that have to occur to keep that cylinder spinning and indexing true.
All that said, I've frequently seen CCW's dry as Egyptian mummies and so caked up with lint that if cartridge ignition WAS realized, the handgun could perform double-duty as a firestarter. Just because you haven't shot it doesn't mean you don't have to occasionally clean it, check all the crevices, and run some basic function checks. Put another way, would you jump out of an airplane with a musty-smelling parachute that has an inspection tag reading "Packed with pride in 1943"?
The flip side is I've seen guys go all "Oil Baron" on their guns - obsessively scrubbing with a river of solvent to render the surfaces they know how to access spotlessly clean. . .but forcing all manner of black sludge into extractor cuts and firing pin channels that the working parts begin to have trouble moving as intended.
And even if you are on the ball in those regards, NONE of that will keep the gremlins out of your ammunition, factory or otherwise.
One nice touch about the show Black Sails is that a lot of the circa-1720 pirates are shooting their flintlock pistols left-handed, presumably because they regarded them as a handy, but largely untrustworthy means of stacking the odds in their favor right before going to work with the much more reliable sharpened steel. It's good that technology has advanced to the point that some folks at times put absolute faith in it, but that doesn't mean doing so is particularly wise. Backup plans are GOOD!