I'm not knocking you by any means. Yes there are some loads for heavies using faster powders than unique but I just can't wrap my head around launching anything over about 260 grains with red dot, tite group, both of which are faster than Unique. There is a load listed for 300gr and 10gr of W231 which is faster still. These are for 44 magnum none listed for 45 Colt I am certain Hogdgon is just steering well clear of anyone dropping one of these wrist rocket loads into a Colt clone.
Back to the point of the post. There is a conspicuous void of heavy boolit/fast powder load data because it comes down to this.. Loading a fast burning powder under a heavy for caliber boolit is ALMOST the same thing as shooting a load into a somewhat obstructed barrel. The heavy boolit takes a LOT of inertia to start it moving, and in this time the pressure curve can go sky high in 1/10th of the time it would take with a slower burning powder. There really is no room for safety, let alone room for error. It's just not good sound principles to cook up such recipes.
Guns are 100% physics. ALL of the laws of physics govern and define reloading and those published guidelines are there because scientific principles associated with the study and implementation of the laws of physics dictate the limits of pressure, velocity, momentum, energy, it's all figured out and then tested and proven with pressure barrels and other tools much more sophisticated for the average handloader to use.
There are GAPS in this information where the limits are reached. They are there because the pursuit of usable data has reached a stopping place. Hence you won't find Unique listed as a suitable powder for a 300gr boolit in 45 Colt. Even in the strong Ruger revolvers, pressure is unpredictable and spiky, this is a KNOWN ATTRIBUTE of this double based powder so nobody publishes data for it. Not to say it cannot be done, but to say it SHOULD NOT be done.