Have you tried using 357 magnum brass for your lower power loads? That 1/10 of an inch additional jump from the 38 Spl brass can't be helping much. A lot has been written above about the basics. Are you loading all 6 chambers? Load 4 or 5, spin the cylinder before you insert it. That way you won't know if you have a cartridge under the hammer or not. This can reveal a lot about form and follow through.