when all else seemingly fails, work some loads as consistently as possible (weigh the powder, NO thrown charges) and lead sled @ 200 yards (100 yards for a .45-70 is too dang short and not a good test of that round) with careful multiple wipings (no blowing) 'tween firings. that might be the eye opener ya need. if not, yer loads and process are not as consistent as ya think - and/or yer gun isn't happy with what yer feeding it.