It depends I guess. If rolling beer cans at 25 yards is you goal. A bullet like the 429421 or the 250k 250kt 245kt all work just fine and are accurate enough for most hunting. If your goal is the best accuracy possible id go to a gas checked design. my favorite is the rcbs 240swcgc. two other great ones are the 429244 and the 429215. If you want heaver the lbt 280 lfngc has been great as has the ballistic cast 300 lfngc. I wont get into the "i get just as good accuracy with a pb bullet argument" Yes ive gotten some guns to shoot real well with plain based bullets but it usually takes at least twice the load development if in fact I do find a load like that. The 240 rcbs has been flat out accurate in every 44 I own and I think you could throw about any powder and primer you wanted in a case and it would at least do as well as any of the plain based bullets.