I have an old memory of a study done by NYPD a couple of decades back. They looked over the records of every police shooting since Teddy Roosevelt was Commissioner. The perps were shot with everything from a 22 Short to a 458 Win. Mag.
The bottom line of the study was where you hit them was far more important than what you hit them with. If the "caliber wars" are not over, it is time they should be. Stay calm and shoot straight!