I have the same concerns here... I have a Danish Remington I'm working up loads for (as well as an 1868 Springfield in .50/70, and an 11mm Mauser).
It's encouraging that people here use Trailboss, and are still alive to tell about it.
The problem that I see, is that you would want to use a powder that mimicks the ignition time and pressure curve of FF or so black powder, so that the receiver doesn't see sudden spikes or other pressure excursions... 4198 does this, I believe 3031 does also.
Trailboss on the other hand, has a pressure curve that spikes about three times higher than FF or 4198... That seems like asking for problems to me...
I'll stick with 4198 loads not to exceed factory, or with FF/1.5F loads here.
These rifles are all 100+ years old, and I don't want to push my luck.
I did see what was left of a blown up RRB several years ago at a gun show: From what I remember, the builder/shooter tried to turn it into some sort of a 30 caliber magnum rifle.
The receiver failed due to excess pressure, but the block didn't (which was why the shooter wound up presumably seriously injured instead of dead).
There has been a thread recently about a Swedish fatality due to firing an unknown high pressure modern cartridge in an old rifle that looked like it was pretty ratty to begin with.
In that case, the block did let go and kill the shooter. Here's the link:
http://castboolits.gunloads.com/show...Block-strenght