I recommend taking an accurate .22 in the spring when the pups are learning. Lots of below 100 yard shots. For me the 22-250 is king between 100-400 yds. Due to mirage and eye fatigue I consider 12x max for me at least. I'm afraid cast bullets will ricochet too much from the hard prairie soil. I've watched .357, .41, & .44 swc's skip and hit the ground like skipping a rock on water! My favorite place was Muleshoe, Texas where my uncle farmed for decades although I've shot them in Wyoming, Colorado, Kansas, Oklahoma, and New Mexico. We found a small town near No Man's Land on the TX/Ok border last fall while scouting for Pronghorn near Dalhart. It brought back memories like the wind going different directions like ole 5 hole mentioned and the fact that a .223 ain't a 22-250 past 300 yards. And I got one that was too curious at 30 yds with a 12 gauge! I wish y'all a wonderful hunt wherever you go.
Best, Thomas.