Regards the OPs question Spence Wolf found the old original mercuric boxer primers used in BP 45-70 loads were very strong (flame strength and duration), as strong as the strongest of our magnum primers of today. He relates this in his very fine book; Loading Cartridges For The Original .45-70 Springfield Rifle And Carbine. Spence also recommends the use of the Federal 215 Magnum LR Primer be used, especially with compressed BP loads. Spence recommends a #41 (.096") or a 3/32" drill be used to open the flash hole. I have done this now for many years with the 45-70 cases I load with BP. I have found no other method to give as good internal ballistics or accuracy when the BP is compressed.
As to drilling out flash holes in rimless case that headspace on the shoulder to prevent the case shoulder setting back and causing headspace problems (misfires and failure to extract) when squib/gallery/cat's sneeze loads are used; testing has consistently proven if there is insufficient psi for the case to expand and grip the chamber walls the power of the primer explosion can set the shoulder back. Over several firings with such loads the case's shoulder will set back far enough to cause misfires and extraction difficulties. This has been proven numerous times by several different individuals.
There are two real benefits to using cases with drilled flash holes if such light squib/gallery/cat's sneeze loads are used; The first is the larger flash hole allows the flash to immediately enter the case interior and does not build pressure in the primer pocket. Thus the case is not pushed forward with the attendant shoulder set back. Well fire formed cases with the flash holes drilled can be fired many, many times w/o any shoulder set back. The second benefit is the emergence of the primer flash into the case interior. With the majority of the flash entering the case at once it better fills the entire case to better ignite the small charges of powder. This is especially beneficial in cases of .300 Savage capacity and larger with the small charges of very fast burning powder normally used in such loads. The flash getting into the case as quick as possible and filling the entire case with flash promotes sure ignition of the small powder charges. It thus negates a great amount of "powder position" problems with when such small charges are used.
Of course headspace problems do not develop with rimmed cases as they headspaced on the rim, not the shoulder. If you repeatedly fire such loads in well fire formed rimmed cases you will probably see a small amount of primer back out after a few firings if the flash holes are not drilled out. This is from the shoulder being set back allowing the rim to bump up against the barrel. Even though there may be a small amount of primer back out the rimmed cases are still properly headspaced and the extraction should not be a problem.
With controlled round feed bolts the same pretty much happens as with rimed cases. The rimless case will also be pushed forward setting the shoulder back if the flash holes are not drilled with such loads. However the rim can only move as far forward as the extractor will allow it. There probably will be a bit of primer set back. Thus with normal firing pin protrusion there isn't a misfire problem and since the rim slips up under the extractor during feeding there shouldn't be any extraction problems.
It's when the squib/gallery/cat's sneeze loads are used with rimless cases in push feed actions that the problem of case headspace shortening develops. The case is constantly under pressure from the ejector pushing it forward in the chamber. If the flash hole is not drilled the primer explosion pushes the cases further and sets the shoulder back After several firings the case in chamber is pushed further and further into the chamber as the shoulder sets back from repeated firings. At some point the firing pin can not effectively crush the primer and a misfire will occur. also the extractor in the bolt may not be able to snap over the rim and extraction may be a problem.
The solution is to drill the flash holes out with a #31 - #28 drill. The #28 is the largest size that will still allow the anvil feet to have something to rest on so the primer compound will be crushed and ignited on it by the firing pin. While I normally keep some cases just for these types of squib/gallery/cat's sneeze loads are used for my push feed actions I have also found the benefit of better internal ballistics and less powder position sensitivity to be such that I also have some rimmed cases (303 and 7.62x54R) with flash holes drilled.
If some worry about the psi increasing I have measured the psi (M43 Oehler) in comparative tests with and with out the flash holes drilled using top end cast bullet loads with 311291s over 4895 powder in the .308W and the 30-06 (2200 and 1950 fps). I found no increase in the average psi and only a very slightly faster rise to peak psi in the cases with drilled flash holes. I've thus been using the cases for both squib/gallery/cat's sneeze loads, intermediate cast bullet loads and normal top end cast bullet loads w/o any problems. With top end loads the internal ballistics are almost always a bit better but accuracy remains pretty much the same.
And no, I am not saying the cases with drilled out flash holes are safe with top end higher pressure jacketed bullet loads because I do not know as I've not tested them for that. I have no real need nor desire to either. However for squib/gallery/cat's sneeze loads the use of cases with drilled flash holes is worth the effort.
Larry Gibson