I've been shootin round balls out of rifles since you could get a 1903-A3 for two months worth of paperboy wages - and if I recall correctly I got the bayonet and other accessories/ammo too... Back then it was mainly about getting reps with my (only) centerfire rifle. Didn't have to travel to a range and at that time a boy riding his bike with a rifle slung across his back was not considered a reason enough to call the police.
I continued the practice and still have the charging (powder scoop) tool made for us by our Scoutmaster through this day though I prefer light for caliber bullets (like the Lyman 311008) as they are accurate at longer ranges.
I continue to use Bullseye (no filler) and even used it in a recent silhouette match. The chickens went down with ease but the Pigs wouldn't reliably go down even with a perfect hit.
I've had better luck in rifles. Handguns tend to print well below the sights.
45 Colt at 25 yards. The three in the bottom are round ball loads.
32 H&R Single Six at 7 yards with round ball.