As to shot placement ~ my very, very, very most favorite shot (yah, I know not proper English) with a slug gun firing a hard deep penetrating cast boolit projectile (whether full bore or saboted) is to shoot on a trajectory line to blow through one or both ball joints of the front shoulder right at the ball joint and blow out the lungs in the process. Often unless its a perfect broadside shot you can only blow out one of the two shoulders plus the lungs, only on a perfect broadside do you get both front shoulders and the lungs. On a quartering away shot you shoot to enter into the lungs behind the facing shoulder on a line that will blow out the off-side front shoulder ball joint with the exit wound and on a quartering towards shot you blow out the facing shoulder ball joint and then blow through the lungs at exit behind the off-side front shoulder. If your shot drops up to six inches lower then you expect it too (always underestimate drop rather then overestimate with this kind of shot) you still get the lungs and maybe even the heart and often still blow through the big top bone in one or both front legs.
Basically, with that kind of shot you both "blow out the boiler room" in the lungs/heart cavity and blow out the front legs where there is the least amount of good meat to wreck while producing instant de-mobilization by blowing out a major muscle joint.
I will also take shots at the back of the neck while they are running away, but only at close range and you have to time the shot with their bouncing run so you squeeze off a quick jerk "bird-shot type" shot rather then a slow long-range slug gun type shot so their neck and forward body is up high in the air and their hind quarters (where a huge amount of the good meat is that you don't want to damage) are down low so you have a triangle shaped kill zone well above their hind quarters and intestinal nasty gut area with the tip of the triangle at the back of their head and the bottom base half way up their body length while they are on the first part of their upwards bounce. The best load for that shot is Tri-Ball or something similar and is best attempted at about 15-35 yards with a red dot type tactical sight, can also be done with a handgun if your good and have a similar sights configuration.
I never, ever, ever, would take a shot on the hind quarters. If its the only shot I've got then that would be a shot I pass up even if its the last 10-minutes of legal shooting hours on the last day of the season and I've still got one tag left. Way too much good meat there and it takes a powerful wallop to actually to enough damage in those large stronger bonier hind quarters compared to the front shoulders which are much more easily busted up and have hardly any good meat on them anyway.
YMMV ~ but that's my $0.02
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GAEP IN iTALY.
